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Product Description
IL-18R polyclonal Antibody | BS7143 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB,IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin’s disease cell lines, and does not bind IL-1α or IL-1β. The association of IL-18 to IL-18R leads to activation of NFκB. At present two subunits of IL-18R have been characterized: IL-18Rα and IL-18Rβ. IL-18Rα has been described as the ligand-binding chain and IL-18Rβ as the signal-transduction chain.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IL-18R polyclonal Antibody detects endogenous levels of IL-18R protein.
Molecular Weight: ~ 75 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CD218 antigen-like family member A; CD218a; CDw218a; CDw218a antigen; IL 1Rrp; IL-18R-1; IL-18R1; IL-1Rrp; IL1 receptor related protein; IL1 receptor-related protein; IL18R_HUMAN; IL18R1; IL18RA; Il18ralpha; IL1R-rp; IL1RRP; Interleukin 18 receptor 1;
Immunogen: Recombinant full length Human IL-18R.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
