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Product Description
ITGA2B polyclonal Antibody | BS7664 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IF
Application Range: WB: 1:500~1:2000 IF: 1:50~1:200
Background: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ITGA2B polyclonal Antibody detects endogenous levels of ITGA2B protein.
Molecular Weight: ~135 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: antigen CD41; BDPLT16; BDPLT2; CD41; cd41 antigen; CD41a; cd41b; form 2; gp2b; GPalpha IIb; gpalphaiib; gpiib; GT; gta; HPA3; Integrin alpha 2b; Integrin alpha IIb; Integrin alpha-IIb light chain; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) ; ITA2B_HUMAN; ITGA2B; ITGAB; platelet fibrinogen receptor alpha; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein iib; platelet specific antigen bak;
Immunogen: Recombinant full length Human ITGA2B.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
