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Product Description
RPL6 polyclonal Antibody | BS8076 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: Mammalian ribosomal proteins are encoded by multigene families that consist of processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein L6, also known as RPL6, TAXREB107 or TXREB1, is a 288 amino acid component of the large ribosomal 60S subunit. Localized to the cytoplasm, Ribosomal Protein L6 binds specifically to domain C of the tax-responsive element (FOXN2) of human T-cell leukemia virus type 1, thereby regulating tax-mediated transcriptional activation. Ribosomal Protein L6 is upregulated in multi-drug resistant (MDR) gastric cancer cells and is implicated in Noonan syndrome, a congenital genetic condition characterized by impaired blood clotting, short stature and indentation of the chest. Two isoforms exist due to alternative splicing events.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: RPL6 polyclonal Antibody detects endogenous levels of RPL6 protein.
Molecular Weight: ~ 33 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: 60S ribosomal protein L6; Neoplasm-related protein C140; Tax-responsive enhancer element-binding protein 107; TaxREB107; RPL6; TXREB1
Immunogen: Recombinant full length Human RPL6.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
