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Product Description
SIN3B polyclonal Antibody | BS5930 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IF
Application Range: WB: 1:500~1:1000 IF: 1:50~1:200
Background: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SIN3B polyclonal Antibody detects endogenous levels of SIN3B protein.
Molecular Weight: ~ 40, 129, 133 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b; KIAA0700
Immunogen: Synthetic peptide, corresponding to amino acids 260-305 of Human SIN3B.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
