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Product Description
WARS polyclonal Antibody | BS7839 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IF
Application Range: WB: 1:500~1:2000 IF: 1:50~1:200
Background: Tryptophanyl-tRNA synthetases are essential enzymes that catalyze the aminoacylation of tRNA (trp) with tryptophan, an essential function of the protein synthesis machinery of the cell. Two forms of tryptophanyl-tRNA synthetase exist: a cytoplasmic form, named TrpRS (also known as WARS), and a mitochondrial form, named WARS2. In normal cells, human TrpRS exists as a full length form and as a truncated form designated mini TrpRS, which is produced by alternative splicing. Expression of mini TrpRs is highly stimulated in human cells by the addition of IFN-gamma. Although both human full-length TrpRS and mini TrpRS are enzymatically active in aminoacylation, they differ in angiostatic activity. The gene encoding human TrpRS maps to chromosome 14q32.31 and the gene encoding human WARS2 maps to chromosome 1p13.3-p13.1. The first 18 amino acids of WARS2 constitute the mitochondrial localization signal sequence.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: WARS polyclonal Antibody detects endogenous levels of WARS protein.
Molecular Weight: ~ 53 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Gamma 2; GAMMA-2; Gamma2; hWRS; IFI 53; IFI53; IFP 53; IFP53; Interferon induced protein 53; Interferon-induced protein 53; SYWC_HUMAN; T2-TrpRS; TrpRS; Tryptophan tRNA ligase, cytoplasmic; Tryptophan tRNA ligase 1 cytoplasmic; Tryptophan tRNA ligase; Tryptophan--tRNA ligase; Tryptophanyl tRNA synthetase; Tryptophanyl tRNA synthetase cytoplasmic; WARS; WARS protein; WRS;
Immunogen: Recombinant full length Human WARS.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
