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Product Description
CPE polyclonal Antibody | BS65337 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IHC-p,IF (paraffin section),ELISA
Application Range: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Background: carboxypeptidase E (CPE) Homo sapiens This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015],
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CPE Polyclonal Antibody detects endogenous levels of CPE protein.
Molecular Weight: ~ 53 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CPE; Carboxypeptidase E; CPE; Carboxypeptidase H; CPH; Enkephalin convertase; Prohormone-processing carboxypeptidase
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human CPE. AA range:427-476
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway:
