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Product Description
SERPINA7 polyclonal Antibody | BS8123 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Background: The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Serpin family members include thyroxine-binding globulin precursor (TBG) . TBG is a serum protein that transports thyroxine, carrying approximately 75% of circulating T4. Inherited de-fects in TBG are associated with three phenotypes based on the level of TBG in serum of affected hemizygous males: complete TBG deficiency (TBG-CD), partial TBG deficiency (TBG-PD) and TBG excess (TBG-E) . TBG is expressed by the liver and secreted in plasma.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SERPINA7 polyclonal Antibody detects endogenous levels of SERPINA7 protein.
Molecular Weight: ~ 46 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Thyroxine-binding globulin; Serpin A7;T4-binding globulin; SERPINA7; TBG
Immunogen: Recombinant full length Human SERPINA7.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Ubiquitin Proteasome,
