Euro
USD
British Pound
NULL
Product Description
SLC6A4 polyclonal Antibody | BS72445 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB,IHC
Application Range: WB 1:2000 - 1:5000 IHC 1:50 - 1:200
Background: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SLC6A4 polyclonal Antibody detects endogenous levels of SLC6A4 protein.
Molecular Weight: ~ 69 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: 5-HTT;5-HTTLPR;5HTT;hSERT;HTT;OCD1;SERT;SERT1
Immunogen: A synthetic peptide of human SLC6A4
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
