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Product Description
Endonuclease G polyclonal Antibody | CAS75127 | Bioworld
Host: Rabbit
Reactivity: Human,Rat,Mouse
Application: WB IP IHC
Application Range: WB: 1:2000~1:5000 IP:1:2000~8000 IHC:1:50~1:100
Background: Endonuclease G (EndoG) is a nuclear-encoded mitochondrial nuclease that has been reported to function in apoptosis, DNA recombination and cell proliferation. EndoG is expressed as a precursor protein containing an amino-terminal mitochondrial targeting sequence which is removed when the protein is imported into the mitochondria. During apoptosis EndoG is released from the mitochondria, translocates to the nucleus and cooperates with other nucleases to trigger DNA fragmentation associated with the apoptotic process
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Endonuclease G polyclonal Antibody detects endogenous levels of Endonuclease G protein.
Molecular Weight: ~ 30 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Endonuclease G, mitochondrial ; Endo G; ENDOG
Immunogen: Recombinant protein of human Endonuclease G.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Mitochondrial Control of Apoptosis,Death Receptor Signaling,
![Endonuclease G (EndoG) Antibody [Polyclonal] | PC-536](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/391497/569960/klogo__76714.1643661101__28204.1644059271.png?c=2 "Endonuclease G (EndoG) Antibody [Polyclonal] | PC-536")
