Quick view Biovision | SGC707 | B2846 SGC707 is a potent, selective and allosteric inhibitor of Protein arginine methyltransferase3 (PRMT3) with an IC₅₀ of 31 nM and KD of 53 nM. It inhibits the methylation of histones in cells at a... MSRP: Was: Now: £606 - £1,918 Choose Options Compare
Quick view Biovision | p-nitro-Pifithrin-α | B2845 p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α. Pifithrin-α is an inhibitor of p53 that blocks p53-dependent apoptosis. p-nitro-Pifithrin-α blocks p53-mediated expression of p21/WAF1... MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Biovision | Acetyl Coenzyme A (sodium salt) | B2844 Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic reactions. It is formed either by the oxidative decarboxylation of pyruvate, β-oxidation of fatty acids or oxidative... MSRP: Was: Now: £346 - £738 Choose Options Compare
Quick view Biovision | AGK7 | B2843 AGK7 is an inactive control and an isomer of AGK2. AGK2 is a cell-permeable, selective inhibitor of SIRT2 which is a NAD+ (nicotinamide adenine dinucleotide)-dependent deacetylase (IC₅₀ = 3.5 µM)... MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Biovision | CAY10685 | B2842 CAY10685 is an active clickable analog of the lysine acetyltransferase inhibitor 4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole (CPTH2 hydrochloride). The alkyne moiety reacts with an... MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Biovision | GSK-J5 (hydrochloride) | B2841 GSK-J5 is an isomer of GSK-J4 and a prodrug for negative control GSK-J2. GSK-J2 is a negative control for GSK-J1, which is an inhibitor of the H3K27 histone demethylases JMJD3 and UTX. GSK-J5 did not... MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Biovision | SAHA-Bpyne | B2840 SAHA-BPyne is a SAHA derivative with a benzophenone crosslinker and an alkyne tag. It is a photoreactive “clickable“ probe. It is used to profile histone deacetylase (HDAC) activities in native... MSRP: Was: Now: £708 - £1,134 Choose Options Compare
Quick view Biovision | Indole-3-carbinol | B2839 Indole-3-carbinol is an anticancer phytochemical in cruciferous vegetables. It is produced by the breakdown of the glucosinolate glucobrassicin by the action of enzyme myrosinase. It induces... MSRP: Was: Now: £346 - £478 Choose Options Compare
Quick view Biovision | 4-pentynoyl-Coenzyme A (trifluoroacetate salt) | B2838 4-pentynoyl-Coenzyme A (trifluoroacetate salt) is an alkyne-derivatized acetyl-CoA reporter. It is metabolically transferred onto lysine residues of proteins by lysine acetyltransferases. It enables... MSRP: Was: Now: £606 - £968 Choose Options Compare
Quick view Biovision | UNC0321 tri(trifluoroacetate salt) | B2837 UNC0321 is an inhibitor of G9a histone methyltransferase (HMTase) with picomolar potency. It is a quinazoline analogue with a Morrison Ki of 63 pM. It inhibits G9a with an IC₅₀ of 6 nM and 9 nM in... MSRP: Was: Now: £346 - £806 Choose Options Compare
Quick view Biovision | Methylstat (hydrate) | B2836 Methylstat is a methyl ester prodrug that inhibits Jumonji C domain-containing histone demethylase (JMJD) in cells. Methylstat inhibits growth of JMJD2C-sensitive oesophageal carcinoma cell line... MSRP: Was: Now: £444 - £1,134 Choose Options Compare
Quick view Biovision | TZ9 | B2835 TZ9 is a triazine analogue inhibitor of human E2 ubiquitin-conjugating enzyme Rad6B/HHR6B. It docks to the Rad6B catalytic site. It inhibits Rad6B-induced histone H2A ubiquitination, downregulates... MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Biovision | 2-Hexyl-4-Pentynoic Acid | B2834 2-Hexyl-4-Pentynoic Acid is an inhibitor of histone deacetylases (HDACs). It is a derivative of Valproic acid. It inhibits HDAC activity with an IC₅₀ of 13 μM, compared to an IC₅₀ of 398 μM for... MSRP: Was: Now: £380 - £640 Choose Options Compare
Quick view Biovision | MPI-5a | B2833 MPI-5a is a potent and selective inhibitor of Histone Deacetylase 6 (HDAC6) with an IC₅₀ of 36 nM. It inhibits the acetylation of tubulin in cells with an IC₅₀ value of 210 nM.MPI-5a is a potent and... MSRP: Was: Now: £508 - £772 Choose Options Compare
Quick view Biovision | HPOB | B2832 HPOB is a hydroxamic acid-based small-molecule that selectively inhibits histone deacetylase 6 (HDAC6). The IC₅₀ for inhibition of recombinant HDAC6 is 56 nM. It inhibits the growth of normal human... MSRP: Was: Now: £380 - £1,066 Choose Options Compare
Quick view Biovision | TCS HDAC6 20b | B2831 TCS HDAC6 20b is an inhibitor of histone deacetylase 6 (HDAC6). It synergistically inhibits the growth of HCT116 cells at a concentration of 5 µM in combination with paclitaxel. It blocks the growth... MSRP: Was: Now: £380 - £1,066 Choose Options Compare
Quick view Biovision | JFD00244 | B2830 JFD00244 is an inhibitor of SIRT2. SIRT2 is a NAD+ (nicotinamide adenine dinucleotide)-dependent deacetylase. A major substrate of SIRT2 is α-tubulin. JFD00244 inhibits SIRT2 with an IC₅₀ of 56.7 µM... MSRP: Was: Now: £346 - £640 Choose Options Compare
Quick view Biovision | (±)-β-Hydroxybutyrate | B2829 (±)-β-Hydroxybutyrate is a ketone body which accumulates in blood during fasting when the liver switches to fatty acid oxidation or in Diabetic Ketoacidosis. It is an inhibitor of class I histone... MSRP: Was: Now: £346 - £640 Choose Options Compare
Quick view Biovision | OAC3 | B2828 OAC3 (Oct4-activating compound3) is an activator of octamer-binding transcription factor 4 (Oct4). Oct4 is an important regulator of embryonic stem cells pluripotency. It is used to generate induced... MSRP: Was: Now: £444 - £1,262 Choose Options Compare
Quick view Biovision | Iberin | B2827 Iberin is a natural isothiocyanate from cruciferous plants. It is a hydrolysis product of glucosinolate. It induces the expression of phase II detoxification enzymes, quinone reductase (QR) and... MSRP: Was: Now: £346 - £806 Choose Options Compare
Quick view Biovision | S-(5'-Adenosyl)-L-methionine chloride (hydrochloride) | B2826 SAM is a ubiquitous methyl donor. It is a cofactor for methyl transferases such as catechol O-methyltransferase (COMT) and DNA methyltransferase. Most of it is present in the liver, where 85% of all... MSRP: Was: Now: £380 - £1,002 Choose Options Compare
Quick view Biovision | 5-Nitroso-8-quinolinol | B2825 5-Nitroso-8-quinolinol is a quinoline inhibitor of histone deacetylase (HDAC). It inhibits HDAC activity in vitro and causes reactive oxygen species, DNA damage and apoptosis in MCF-7 breast cancer... MSRP: Was: Now: £346 - £806 Choose Options Compare
Quick view Biovision | Sinefungin | B2824 Sinefungin is a natural nucleoside and a structural analog of S-adenosylmethionine (SAM). It inhibits SAM-dependent nucleic acid methyltransferases and exhibits antifungal, antiviral, and... MSRP: Was: Now: £478 - £708 Choose Options Compare
Quick view Biovision | UNC0224 | B2823 UNC0224 is a selective G9a Histone Methyltransferase inhibitor. G9a methylates Histone H3 lysine 9, which is required for early embryogenesis. UNC0224 inhibits G9a with an IC₅₀ of 15 nM. It also... MSRP: Was: Now: £380 - £968 Choose Options Compare
Quick view Biovision | 2',3',5'-triacetyl-5-Azacytidine | B2822 2',3',5'-triacetyl-5-Azacytidine is an oral prodrug form of 5-Azacytidine. 5-Azacytidine is an inhibitor of DNA methyltransferase, which can reverse epigenetically silenced genes... MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Biovision | HNHA | B2821 HNHA is an inhibitor of Histone deacetylase (HDAC). It inhibited proliferation of HT1080 human fibrosarcoma cells with an IC₅₀ of 7.5 μM. It induced hyperacetylation, upregulation of p21... MSRP: Was: Now: £380 - £968 Choose Options Compare
Quick view Biovision | KD 5170 | B2820 KD 5170 is a broad spectrum, classes I and II HDAC (histone deacetylase) inhibitor. The IC₅₀ for inhibition of HDAC1, HDAC2, HDAC3, HDAC4 is 0.02 μM, 2 μM, 0.075 μM, 0.026 μM respectively, in vitro... MSRP: Was: Now: £380 - £968 Choose Options Compare
Quick view Biovision | CAY10603 | B2819 CAY10603 is a selective inhibitor of Histone deacetylase 6 (HDAC6). The IC₅₀ for inhibition of HDAC6 is 2 pM, in vitro. CAY10603 inhibited growth of various pancreatic cell lines with IC₅₀ values... MSRP: Was: Now: £674 - £2,116 Choose Options Compare
Quick view Biovision | Tenovin-6 | B2818 Tenovin-6 is a SirT2 inhibitor and a p53 activator. It is a water-soluble analog of Tenovin-1. Tenovins inhibit the protein-deacetylase activities of SirT1 and SirT2. The IC₅₀ for inhibiting human... MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Biovision | Butyrolactone 3 | B2817 Butyrolactone 3 is an inhibitor of histone acetyltransferase (HAT) Gcn5. Gcn5 acetylates histones H2B and H3. Butyrolactone 3 inhibits Gcn5 with an IC₅₀ value of 100 μM. It has an affinity to the... MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Biovision | MI-nc (hydrochloride) | B2816 MI-nc (hydrochloride) is a weak inhibitor of the menin-MLL interaction. Menin is a tumor suppressor protein. Menin is a part of the MLL (Mixed Lineage Leukemia) SET1-like histone methyl transferase... MSRP: Was: Now: £444 - £1,262 Choose Options Compare
Quick view Biovision | CPTH2 (hydrochloride) | B2815 CPTH2 (hydrochloride) is an inhibitor of Histone Acetyltransferase (HAT) activity of Gcn5. Gcn5 acetylates histones H2B and H3. CPTH2 inhibited HAT reaction in vitro and it decreased acetylation of... MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Biovision | Lysine-specific Demethylase Inhibitor (1C) (Hydrochloride) | B2814 Lysine-specific Demethylase Inhibitor (1C) inhibits Lysine-specific demethylase 1 (LSD1). LSD1 removes methyl groups from histones. The inhibitor LSD 1C increased H3K4me1 and H3K4me2, without... MSRP: Was: Now: £380 - £968 Choose Options Compare
Quick view Biovision | GSK-J2 (Sodium Salt) | B2813 GSK-J2 (sodium salt) is an isomer of GSK-J1. GSK-1 is a selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX, with an IC₅₀ of 60 nM for human JMJD3 in vitro. GSK-J2 poorly inhibits... MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Biovision | L-α-Hydroxyglutaric Acid Disodium Salt | B2812 L-α-Hydroxyglutaric Acid is metabolized to 2-oxoglutarate or α-ketoglutarate by L-2-hydroxyglutarate dehydrogenase. Rare defects in L-2-hydroxyglutarate dehydrogenase cause a neurometabolic disorder... MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Biovision | Wedelolactone | B2811 Wedelolactone is a natural coumestan that irreversibly inhibits IKK in NF-κB signaling pathway. IKK phosphorylates the IκBα protein, which results in the degradation and dissociation of IκBα from... MSRP: Was: Now: £410 - £968 Choose Options Compare
Quick view Biovision | BRD9539 | B2810 BRD9539 is a specific inhibitor of euchromatin histone methyltransferase G9a (EHMT2). EHMT2 catalyzes the methylation of lysine 9 on histone H3. BRD9539 inhibits EHMT2 with an IC₅₀ of 6.3 μM. It also... MSRP: Was: Now: £346 - £806 Choose Options Compare
Quick view Biovision | 2,4-Pyridinedicarboxylic Acid | B2809 2,4-Pyridinedicarboxylic Acid is an inhibitor of histone lysine demethylases and 2-oxoglutarate oxygenases. It structurally mimics 2-oxoglutarate (2-OG) and chelates zinc, thus inhibiting a range of... MSRP: Was: Now: £346 - £738 Choose Options Compare
Quick view Biovision | PRMT4/CARM1 Inhibitor | B2808 PRMT4/CARM1 Inhibitor is highly selective in blocking the activity of Protein Arginine Methyltransferase 4/Coactivator-Associated Arginine Methyltransferase 1. The IC₅₀ value of inhibition is 7.1 µM... MSRP: Was: Now: £542 - £836 Choose Options Compare
Quick view Biovision | Delphinidin (chloride) | B2807 Delphinidin is a natural plant pigment. It serves as the precursor of certain anthocyanins. It is used as an anthocyanin standard.The pigment is found in grapes, cranberries, and some flowers. It is... MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Biovision | CAY10669 | B2806 CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor). The IC₅₀ for inhibition of PCAF is 662 μM. CAY10669 at 30-60 μM concentration... MSRP: Was: Now: £606 - £1,788 Choose Options Compare
Quick view Biovision | Coumarin-SAHA | B2805 Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor. It is a fluorescent probe that competitively binds HDAC. It is a SAHA derivative where the... MSRP: Was: Now: £346 - £806 Choose Options Compare
Quick view Biovision | JGB1741 | B2804 JGB1741 is a small molecule inhibitor of SIRT1. The sirtuins (SIRTs) are NAD+-dependent histone deacetylases. The IC₅₀ value of JGB1741 in a cell-free assay is 15 μM. The IC₅₀ for cell proliferation... MSRP: Was: Now: £478 - £1,362 Choose Options Compare
Quick view Biovision | F-Amidine (trifluoroacetate salt) | B2803 F-Amidine (trifluoroacetate salt) is an irreversible inhibitor of protein arginine deiminase (PAD). The in vitro IC₅₀ values are 29.5 µM, 350 µM, and 21.6 µM for PAD1, PAD3 and PAD4, respectively... MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Biovision | Cl-Amidine (hydrochloride) | B2802 Cl-Amidine (hydrochloride) is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor. It catalyzes the post-translational modification of arginine residues on histones to form citrulline. The... MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Biovision | Sulforaphane | B2801 Sulforaphane is an isothiocyanate found in cruciferous vegetables such as broccoli. It has anti-cancer activity and targets multiple pathways in cancer development. It induces chemopreventative... MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Biovision | 4-Iodo-SAHA | B2800 4-iodo-SAHA is a hydrophobic derivative of the class I and class II HDAC (histone deacetylase) inhibitor SAHA. At 1 μM it demonstrates >60% inhibition of HDAC1 and HDAC6 activity in a deacetylase... MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Biovision | DFHBI-1T | B2799 DFHBI-1T is a mimic of green fluorescent protein (GFP) fluorophore for imaging RNA in living cells. Fluorescence is activated by binding to Spinach2 or Broccoli aptamers. Displays peak excitation... MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Biovision | BI | B2798 BI is a derivative of DFHBI (Cat. No. B2797) that binds Broccoli™ with higher affinity and deliver improved cellular fluorescence. In cells, BI has been found to stabilize the Broccoli™ structure and... MSRP: Was: Now: £1,066 - £1,788 Choose Options Compare
Quick view Biovision | DFHBI | B2797 DFHBI is a cell-permeable non-fluorescent small molecule derived from the GFP chromophore. Upon binding to the “Spinach™” aptamer, DFHBI is converted to a highly fluorescent state that can be... MSRP: Was: Now: £708 - £2,296 Choose Options Compare
Quick view Biovision | Zalcitabine | B2796 Zalcitabine is an antiviral pyrimidine nucleoside analog effective against HIV replication. In cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV... MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Biovision | Sotrastaurin | B2795 Sotrastaurin (AEB071) is a potent pan-PKC (Protein Kinase C) inhibitor, with Kis of 0.22 nM, 0.64 nM, 0.95 nM, 1.8 nM, 2.1 nM and 3.2 nM for PKCθ, PKCβ, PKCα, PKCη, PKCδ and PKCε, respectively... MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Details Biovision | p-nitro-Pifithrin-α | B2845 MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Details Biovision | Acetyl Coenzyme A (sodium salt) | B2844 MSRP: Was: Now: £346 - £738 Choose Options Compare
Quick view Details Biovision | GSK-J5 (hydrochloride) | B2841 MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Details Biovision | SAHA-Bpyne | B2840 MSRP: Was: Now: £708 - £1,134 Choose Options Compare
Quick view Details Biovision | Indole-3-carbinol | B2839 MSRP: Was: Now: £346 - £478 Choose Options Compare
Quick view Details Biovision | 4-pentynoyl-Coenzyme A (trifluoroacetate salt) | B2838 MSRP: Was: Now: £606 - £968 Choose Options Compare
Quick view Details Biovision | UNC0321 tri(trifluoroacetate salt) | B2837 MSRP: Was: Now: £346 - £806 Choose Options Compare
Quick view Details Biovision | Methylstat (hydrate) | B2836 MSRP: Was: Now: £444 - £1,134 Choose Options Compare
Quick view Details Biovision | 2-Hexyl-4-Pentynoic Acid | B2834 MSRP: Was: Now: £380 - £640 Choose Options Compare
Quick view Details Biovision | TCS HDAC6 20b | B2831 MSRP: Was: Now: £380 - £1,066 Choose Options Compare
Quick view Details Biovision | (±)-β-Hydroxybutyrate | B2829 MSRP: Was: Now: £346 - £640 Choose Options Compare
Quick view Details Biovision | S-(5'-Adenosyl)-L-methionine chloride (hydrochloride) | B2826 MSRP: Was: Now: £380 - £1,002 Choose Options Compare
Quick view Details Biovision | 5-Nitroso-8-quinolinol | B2825 MSRP: Was: Now: £346 - £806 Choose Options Compare
Quick view Details Biovision | 2',3',5'-triacetyl-5-Azacytidine | B2822 MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Details Biovision | Tenovin-6 | B2818 MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Details Biovision | Butyrolactone 3 | B2817 MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Details Biovision | MI-nc (hydrochloride) | B2816 MSRP: Was: Now: £444 - £1,262 Choose Options Compare
Quick view Details Biovision | CPTH2 (hydrochloride) | B2815 MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Details Biovision | Lysine-specific Demethylase Inhibitor (1C) (Hydrochloride) | B2814 MSRP: Was: Now: £380 - £968 Choose Options Compare
Quick view Details Biovision | GSK-J2 (Sodium Salt) | B2813 MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Details Biovision | L-α-Hydroxyglutaric Acid Disodium Salt | B2812 MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Details Biovision | Wedelolactone | B2811 MSRP: Was: Now: £410 - £968 Choose Options Compare
Quick view Details Biovision | 2,4-Pyridinedicarboxylic Acid | B2809 MSRP: Was: Now: £346 - £738 Choose Options Compare
Quick view Details Biovision | PRMT4/CARM1 Inhibitor | B2808 MSRP: Was: Now: £542 - £836 Choose Options Compare
Quick view Details Biovision | Delphinidin (chloride) | B2807 MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Details Biovision | Coumarin-SAHA | B2805 MSRP: Was: Now: £346 - £806 Choose Options Compare
Quick view Details Biovision | F-Amidine (trifluoroacetate salt) | B2803 MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Details Biovision | Cl-Amidine (hydrochloride) | B2802 MSRP: Was: Now: £380 - £904 Choose Options Compare
Quick view Details Biovision | Sulforaphane | B2801 MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Details Biovision | 4-Iodo-SAHA | B2800 MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Details Biovision | Zalcitabine | B2796 MSRP: Was: Now: £410 - £1,066 Choose Options Compare
Quick view Details Biovision | Sotrastaurin | B2795 MSRP: Was: Now: £380 - £904 Choose Options Compare