Quick view Biovision | IOX2 | 9451 IOX-2 is a potent, cell-permeable and selective inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC₅₀ = 21 nM). It displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and... MSRP: Was: Now: $837 - $2,440 Choose Options Compare
Quick view Biovision | CH5132799 | B1669 CH5132799 is an inhibitor of class I phosphatidylinositol 3-kinase (PI3K) with IC50 value of 14nM against PI3Kα.CH5132799 is an inhibitor of class I phosphatidylinositol 3-kinase (PI3K) with IC50... MSRP: Was: Now: $865 - $2,587 Choose Options Compare
Quick view Biovision | KN-93 | 2524 Cell-permeable. KN-93 is a potent inhibitor of Ca²⁺/calmodulin-dependent kinase type II (CaM kinase II) (IC₅₀ = 0.37 μM). It does not affect the activities of PKA, PKC, MLCK, or... MSRP: Was: Now: $718 - $1,582 Choose Options Compare
Quick view Biovision | Ertugliflozin | B1896 Ertugliflozin is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2(SGLT2); increases the excretion of glucose with a 2,000-fold selectivity over SGLT1 (IC₅₀ = 0.877 and... MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare
Quick view Biovision | CHIR-090 | B1852 CHIR-090 is a potent, low, tight-binding inhibitor of LpxC (UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase) (Ki = 4.0 nM). Antibacterial agentCHIR-090 is a potent, low,... MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare
Quick view Biovision | Cabazitaxel | B2399 Cabazitaxel is a second generation semisynthetic taxane derived from 10-deacetylbaccatin with potent anticancer activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of... MSRP: Was: Now: $718 - $1,866 Choose Options Compare
Quick view Biovision | Triciribine | 1707 Cell-permeable. A synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 and -3 but... MSRP: Now: $1,120 Add to Cart Compare Quick view Biovision | Roflumilast | 2675 Roflumilast is a selective phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 0.8 nM). Displays anti-inflammatory properties.Roflumilast is a selective phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 0.8 nM)... MSRP: Was: Now: $777 - $2,209 Choose Options Compare Quick view Biovision | PF-04447943 | B1264 PF-04447943 is a potent, brain-penetrant and selective inhibitor of PDE9 (Phosphodiesterase 9) (Ki of 2.8, 4.5 and 18 nM for human, rhesus and rat recombinant PDE9 respectively). Displays high... MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Biovision | SL327 | B1694 SL-327 is a selective inhibitor of MEK1 and MEK2 with IC50 value of 0.18 and 0.22 μM, respectively.SL-327 is a selective inhibitor of MEK1 and MEK2 with IC50 value of 0.18 and 0.22 μM, respectively... MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Biovision | MK-0557 | B2317 A potent and selective antagonist of the neuropeptide Y (NPY) receptor Y5. It is >7,500-fold selective for Y5 over other receptors and lacks activity in a panel of 180 receptors, enzymes, and ion... MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare Quick view Biovision | Empagliflozin | 2877 Empagliflozin is a potent and selective SGLT-2 (sodium glucose co-transporter-2) inhibitor (IC₅₀ of 3.1 nM); displays >300-fold selectivity over SGLT-1, 4, 5 and 6. Antidiabetic agent.Empagliflozin... MSRP: Was: Now: $1,008 - $2,555 Choose Options Compare Quick view Biovision | Tazarotene | B1812 Tazarotene is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis, acne vulgaris and photoaging. Tazarotene induces the expression of tazarotene-induced gene 3... MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Biovision | Fenretinide | 9417 Fenretinide is a Vitamin A acid analog that displays antioxidant and antiproliferative activity. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell... MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare Quick view Biovision | Forskolin | 1531 Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP.Forskolin is an activator of adenylate cyclase leading to an increase in the intracellular concentration... MSRP: Was: Now: $809 - $2,209 Choose Options Compare Quick view Biovision | Tetrahydrouridine | 1671 A competitive cytidine deaminase inhibitor and multidrug resistance modulator. Makes tumor cells more sensitive to radiation therapy making it useful for cancer treatmentTetrahydrouridine is a... MSRP: Was: Now: $1,152 - $20,440 Choose Options Compare Quick view Biovision | CVT-313 | B1137 CVT-313 is a potent and selective inhibitor of CDK2 (cyclin dependent kinase 2) arresting cell growth with IC₅₀ ranging from 1.25 to 20 µM. The Inhibition is competitive with respect to ATP (Ki = 95... MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Biovision | TG003 | 1905 Cell-permeable. A potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (Clk) (Ki = 10 nM for mClk1/Sty; IC₅₀ = 20 nM, 200 nM, >10 µM, and 15 nM for mClk1, mClk2, mClk3, and... MSRP: Was: Now: $865 - $2,499 Choose Options Compare Quick view Biovision | Etoricoxib | B1983 Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent and specific cyclooxygenase-2 (COX-2) inhibitor.Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) that... MSRP: Was: Now: $777 - $2,156 Choose Options Compare Quick view Biovision | RI-1 | B1823 RI-1 is a potent and selective inhibitor of RAD51 (IC₅₀ = 5-30 μM). It specifically reduces gene conversion in human cells and stimulates single strand annealing. It covalently binds to Cys319 on the... MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Biovision | Baricitinib | 2842 Baricitinib is a selective JAK1 and JAK2 inhibitor with IC₅₀ values of 5.9 nM and 5.7 nM, respectively. Baricitinib is ~70 and ~10-fold selective versus JAK3 and Tyk2, with no inhibition to c-Met and... MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Biovision | WP1066 | 1809 A potent, cell-permeable JAK2 inhibitor. A novel analog of the JAK2 inhibitor AG490 (Cat. No. 1570-5) that blocks STAT3 and phosphoinositide-3-kinase pathways. It is significantly more potent and... MSRP: Was: Now: $865 - $2,555 Choose Options Compare Quick view Biovision | Ivermectin | 2721 Ivermectin is an antiparasitic agent. It acts as a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.Ivermectin... MSRP: Was: Now: $665 - $1,411 Choose Options Compare Quick view Biovision | Eltrombopag | 9489 Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet... MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Biovision | Dynasore | 1900 Cell-permeable. A reversible, noncompetitive inhibitor of dynamin that interferes in vitro with the GTPase activity of dynamin1, dynamin2, and Drp1, the mitochondrial dynamin, but not of other small... MSRP: Was: Now: $665 - $1,523 Choose Options Compare Quick view Biovision | Skepinone-L | B1110 Skepinone-L is a potent, ATP-competitive inhibitor of p38 MAPK isoform p38α (IC₅₀ = 5 nM) and p38β (97% inhibition at 1 µM). It has little effect on a range of other kinases, including p38γ and p38δ... MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Biovision | Vesnarinone | B2008 Vesnarinone is a novel inotropic agent that displays unique and complex mechanisms of action. It inhibits phosphodiesterase, thereby leading to increased intracellular calcium, and also affects... MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare Quick view Biovision | Vonoprazan fumarate | B2292 Vonoprazan fumarate is a Potassium-competitive acid blocker (P-CAB) that inhibits gastric H⁺/K⁺ATPase (IC₅₀ = 17 nM) but does not inhibit porcine Na+/K+ ATPase activity when used at a concentration... MSRP: Was: Now: $718 - $1,582 Choose Options Compare Quick view Biovision | CZC24832 | B1676 CZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154... MSRP: Was: Now: $949 - $2,870 Choose Options Compare Quick view Biovision | Prasugrel | 9472 Prasugrel is novel thienopyridine antiplatelet prodrug that is metabolized to the thiol-containing active metabolite R-138727,which binds to and irreversibly inhibits the platelet P2Y12ADP receptor... MSRP: Was: Now: $718 - $1,985 Choose Options Compare Quick view Biovision | E-64 | 1739 E-64 is an irreversible, cell-permeable, potent, and highly selective cysteine protease inhibitor. E-64 will not inhibit serine proteases (except trypsin) like other cysteine protease inhibitors,... MSRP: Was: Now: $1,036 - $2,930 Choose Options Compare Quick view Biovision | Epothilone D | 9559 Epothilone D is a natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the... MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Biovision | UNC0638 | 1933 Cell-permeable. UNC0638 is a potent G9a HMTase inhibitor, exhibiting an IC₅₀ value of MSRP: Was: Now: $749 - $1,463 Choose Options Compare Quick view Biovision | WAY-600 | B1731 WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold)... MSRP: Was: Now: $837 - $1,866 Choose Options Compare Quick view Biovision | WYE-687 | B1730 WYE-687 is an ATP-competitive and selective inhibitor of mTOR with an IC50 value of 7 nM.WYE-687 is an ATP-competitive and selective inhibitor of mTOR with an IC50 value of 7 nM.Biovision | B1730 |... MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare Quick view Biovision | BMS-911543 | 2630 BMS-911543 is a potent and selective JAK2 inhib itor. It displays potent anti-proliferative and pharmacodynamic effects in cell lines dependent upon JAK2 signaling, and has little activity in cell... MSRP: Was: Now: $777 - $2,209 Choose Options Compare Quick view Biovision | CP-640186 | 9422 CP-640186 is a mixed ACC (Acetyl-CoA carboxylase) inhibitor (ACC-1 IC₅₀ = 53 nM; ACC-2 IC₅₀ = 61 nM) that lowers malonyl-CoA levels and inhibits hepatic fatty acid and triglyceride synthesis in vitro... MSRP: Was: Now: $1,008 - $2,958 Choose Options Compare Quick view Biovision | Tiplaxtinin | B1634 Tiplaxtinin(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 µM.Tiplaxtinin(PAI-039) is a selective and orally efficacious... MSRP: Was: Now: $865 - $2,587 Choose Options Compare Quick view Biovision | JZL195 | B1064 JZL195 is a potent dual inhibitor of Monoacylglycerol lipase (MAGL) (IC₅₀ = 2 nM) and fatty acid amide hydrolase (FAAH) (IC₅₀ = 4 nM), enzymes that degrade the endocannabinoids 2-arachidonoylglycerol... MSRP: Was: Now: $777 - $2,209 Choose Options Compare Quick view Biovision | GDC-0349 | B1729 GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki value of 3.8 nM.GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki value of 3.8 nM.Biovision |... MSRP: Was: Now: $837 - $1,866 Choose Options Compare Quick view Biovision | GSK2636771 | 2793 GSK2636771 is a potent, PI3Kβ-selective inhibitor, sensitive to PTEN cell lines.GSK2636771 is a potent, PI3Kβ-selective inhibitor, sensitive to PTEN cell lines.Biovision | 2793 | GSK2636771... MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare Quick view Biovision | Alpelisib | B1271 Alpelisib (also known as BYL719), is a potent and selective phosphatidylinositol-3 kinase α inhibitor. It inhibits P110α, p110β, p110δ, and p110g with IC₅₀ values of 5 nM, 1.2 µM, 0.29 µM and 0.25... MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Biovision | Geldanamycin | 1564 A potent antitumor antibiotic . Binds specifically to heat shock protein HSP90 and its GP96 homologue; inhibits protein maturation.Geldanamycin is a potent antitumor antibiotic . Binds specifically... MSRP: Was: Now: $777 - $2,065 Choose Options Compare Quick view Biovision | EPZ004777 | 2381 A potent and selective DOT1L inhibitor. Treatment of leukemic cells with EPZ004777 results in selective killing of those cells bearing the MLL (mixed lineage leukemia) gene translocation, with little... MSRP: Was: Now: $949 - $2,555 Choose Options Compare Quick view Biovision | MI-3 | B1834 MI-3 is a Menin-MLL (Mixed linage leukemia) protein interaction inhibitor with an IC₅₀ of 648 ± 25 nM. MLL protein is a histone methyltransferase that positively regulates gene transcription... MSRP: Was: Now: $1,061 - $3,385 Choose Options Compare Quick view Biovision | MI-2 | B1835 MI-2 is a Menin-MLL (Mixed linage leukemia) protein interaction inhibitor with an IC₅₀ of 0.45 μM. MLL protein is a histone methyltransferase that positively regulates gene transcription. However,... MSRP: Was: Now: $1,061 - $3,385 Choose Options Compare Quick view Biovision | Repaglinide | B2110 Repaglinide is an antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which... MSRP: Was: Now: $718 - $1,925 Choose Options Compare Quick view Biovision | Glibenclamide | 1878 Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin... MSRP: Was: Now: $690 - $980 Choose Options Compare Quick view Biovision | PF-04691502 | 2289 A potent, ATP-competitive PI3K/mTOR dual inhibitor with broad antitumor activity. PF-04691502 potently inhibits recombinant class I PI3K and mTOR in biochemical assays and suppresses transformation... MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Biovision | Ro3280 | B1175 RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1 (IC₅₀ = 3 nM).RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1 (IC₅₀ = 3 nM).Biovision | B1175 |... MSRP: Was: Now: $1,239 - $4,018 Choose Options Compare Quick view Biovision | Staurosporine | 1048 Potent inhibitor of protein kinase C and most other kinases, including tyrosine kinases. Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site... MSRP: Was: Now: $949 - $2,209 Choose Options Compare Quick view Biovision | Lonafarnib | B1616 Lonafarnib (SCH 66336) is a selectively farnesyltransferase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.Lonafarnib (SCH 66336) is a selectively... MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Details Biovision | IOX2 | 9451 MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Details Biovision | CH5132799 | B1669 MSRP: Was: Now: $865 - $2,587 Choose Options Compare Quick view Details Biovision | KN-93 | 2524 MSRP: Was: Now: $718 - $1,582 Choose Options Compare Quick view Details Biovision | Ertugliflozin | B1896 MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare Quick view Details Biovision | CHIR-090 | B1852 MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare Quick view Details Biovision | Cabazitaxel | B2399 MSRP: Was: Now: $718 - $1,866 Choose Options Compare Quick view Details Biovision | Triciribine | 1707 MSRP: Now: $1,120 Add to Cart Compare Quick view Details Biovision | Roflumilast | 2675 MSRP: Was: Now: $777 - $2,209 Choose Options Compare Quick view Details Biovision | PF-04447943 | B1264 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Details Biovision | SL327 | B1694 MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Details Biovision | MK-0557 | B2317 MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare Quick view Details Biovision | Empagliflozin | 2877 MSRP: Was: Now: $1,008 - $2,555 Choose Options Compare Quick view Details Biovision | Tazarotene | B1812 MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Details Biovision | Fenretinide | 9417 MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare Quick view Details Biovision | Forskolin | 1531 MSRP: Was: Now: $809 - $2,209 Choose Options Compare Quick view Details Biovision | Tetrahydrouridine | 1671 MSRP: Was: Now: $1,152 - $20,440 Choose Options Compare Quick view Details Biovision | CVT-313 | B1137 MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Details Biovision | TG003 | 1905 MSRP: Was: Now: $865 - $2,499 Choose Options Compare Quick view Details Biovision | Etoricoxib | B1983 MSRP: Was: Now: $777 - $2,156 Choose Options Compare Quick view Details Biovision | RI-1 | B1823 MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Details Biovision | Baricitinib | 2842 MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Details Biovision | WP1066 | 1809 MSRP: Was: Now: $865 - $2,555 Choose Options Compare Quick view Details Biovision | Ivermectin | 2721 MSRP: Was: Now: $665 - $1,411 Choose Options Compare Quick view Details Biovision | Eltrombopag | 9489 MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Details Biovision | Dynasore | 1900 MSRP: Was: Now: $665 - $1,523 Choose Options Compare Quick view Details Biovision | Skepinone-L | B1110 MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Details Biovision | Vesnarinone | B2008 MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare Quick view Details Biovision | Vonoprazan fumarate | B2292 MSRP: Was: Now: $718 - $1,582 Choose Options Compare Quick view Details Biovision | CZC24832 | B1676 MSRP: Was: Now: $949 - $2,870 Choose Options Compare Quick view Details Biovision | Prasugrel | 9472 MSRP: Was: Now: $718 - $1,985 Choose Options Compare Quick view Details Biovision | E-64 | 1739 MSRP: Was: Now: $1,036 - $2,930 Choose Options Compare Quick view Details Biovision | Epothilone D | 9559 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Details Biovision | UNC0638 | 1933 MSRP: Was: Now: $749 - $1,463 Choose Options Compare Quick view Details Biovision | WAY-600 | B1731 MSRP: Was: Now: $837 - $1,866 Choose Options Compare Quick view Details Biovision | WYE-687 | B1730 MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare Quick view Details Biovision | BMS-911543 | 2630 MSRP: Was: Now: $777 - $2,209 Choose Options Compare Quick view Details Biovision | CP-640186 | 9422 MSRP: Was: Now: $1,008 - $2,958 Choose Options Compare Quick view Details Biovision | Tiplaxtinin | B1634 MSRP: Was: Now: $865 - $2,587 Choose Options Compare Quick view Details Biovision | JZL195 | B1064 MSRP: Was: Now: $777 - $2,209 Choose Options Compare Quick view Details Biovision | GDC-0349 | B1729 MSRP: Was: Now: $837 - $1,866 Choose Options Compare Quick view Details Biovision | GSK2636771 | 2793 MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare Quick view Details Biovision | Alpelisib | B1271 MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Details Biovision | Geldanamycin | 1564 MSRP: Was: Now: $777 - $2,065 Choose Options Compare Quick view Details Biovision | EPZ004777 | 2381 MSRP: Was: Now: $949 - $2,555 Choose Options Compare Quick view Details Biovision | MI-3 | B1834 MSRP: Was: Now: $1,061 - $3,385 Choose Options Compare Quick view Details Biovision | MI-2 | B1835 MSRP: Was: Now: $1,061 - $3,385 Choose Options Compare Quick view Details Biovision | Repaglinide | B2110 MSRP: Was: Now: $718 - $1,925 Choose Options Compare Quick view Details Biovision | Glibenclamide | 1878 MSRP: Was: Now: $690 - $980 Choose Options Compare Quick view Details Biovision | PF-04691502 | 2289 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Details Biovision | Ro3280 | B1175 MSRP: Was: Now: $1,239 - $4,018 Choose Options Compare Quick view Details Biovision | Staurosporine | 1048 MSRP: Was: Now: $949 - $2,209 Choose Options Compare Quick view Details Biovision | Lonafarnib | B1616 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Previous 182 183 184 185 186 187 188 189 190 191 192 Next Previous 182 183 184 185 186 187 188 189 190 191 192 Next Compare Selected
Quick view Biovision | Roflumilast | 2675 Roflumilast is a selective phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 0.8 nM). Displays anti-inflammatory properties.Roflumilast is a selective phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 0.8 nM)... MSRP: Was: Now: $777 - $2,209 Choose Options Compare
Quick view Biovision | PF-04447943 | B1264 PF-04447943 is a potent, brain-penetrant and selective inhibitor of PDE9 (Phosphodiesterase 9) (Ki of 2.8, 4.5 and 18 nM for human, rhesus and rat recombinant PDE9 respectively). Displays high... MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare
Quick view Biovision | SL327 | B1694 SL-327 is a selective inhibitor of MEK1 and MEK2 with IC50 value of 0.18 and 0.22 μM, respectively.SL-327 is a selective inhibitor of MEK1 and MEK2 with IC50 value of 0.18 and 0.22 μM, respectively... MSRP: Was: Now: $837 - $2,440 Choose Options Compare
Quick view Biovision | MK-0557 | B2317 A potent and selective antagonist of the neuropeptide Y (NPY) receptor Y5. It is >7,500-fold selective for Y5 over other receptors and lacks activity in a panel of 180 receptors, enzymes, and ion... MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare
Quick view Biovision | Empagliflozin | 2877 Empagliflozin is a potent and selective SGLT-2 (sodium glucose co-transporter-2) inhibitor (IC₅₀ of 3.1 nM); displays >300-fold selectivity over SGLT-1, 4, 5 and 6. Antidiabetic agent.Empagliflozin... MSRP: Was: Now: $1,008 - $2,555 Choose Options Compare
Quick view Biovision | Tazarotene | B1812 Tazarotene is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis, acne vulgaris and photoaging. Tazarotene induces the expression of tazarotene-induced gene 3... MSRP: Was: Now: $949 - $2,898 Choose Options Compare
Quick view Biovision | Fenretinide | 9417 Fenretinide is a Vitamin A acid analog that displays antioxidant and antiproliferative activity. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell... MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare
Quick view Biovision | Forskolin | 1531 Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP.Forskolin is an activator of adenylate cyclase leading to an increase in the intracellular concentration... MSRP: Was: Now: $809 - $2,209 Choose Options Compare
Quick view Biovision | Tetrahydrouridine | 1671 A competitive cytidine deaminase inhibitor and multidrug resistance modulator. Makes tumor cells more sensitive to radiation therapy making it useful for cancer treatmentTetrahydrouridine is a... MSRP: Was: Now: $1,152 - $20,440 Choose Options Compare
Quick view Biovision | CVT-313 | B1137 CVT-313 is a potent and selective inhibitor of CDK2 (cyclin dependent kinase 2) arresting cell growth with IC₅₀ ranging from 1.25 to 20 µM. The Inhibition is competitive with respect to ATP (Ki = 95... MSRP: Was: Now: $837 - $2,440 Choose Options Compare
Quick view Biovision | TG003 | 1905 Cell-permeable. A potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (Clk) (Ki = 10 nM for mClk1/Sty; IC₅₀ = 20 nM, 200 nM, >10 µM, and 15 nM for mClk1, mClk2, mClk3, and... MSRP: Was: Now: $865 - $2,499 Choose Options Compare
Quick view Biovision | Etoricoxib | B1983 Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent and specific cyclooxygenase-2 (COX-2) inhibitor.Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) that... MSRP: Was: Now: $777 - $2,156 Choose Options Compare
Quick view Biovision | RI-1 | B1823 RI-1 is a potent and selective inhibitor of RAD51 (IC₅₀ = 5-30 μM). It specifically reduces gene conversion in human cells and stimulates single strand annealing. It covalently binds to Cys319 on the... MSRP: Was: Now: $949 - $2,898 Choose Options Compare
Quick view Biovision | Baricitinib | 2842 Baricitinib is a selective JAK1 and JAK2 inhibitor with IC₅₀ values of 5.9 nM and 5.7 nM, respectively. Baricitinib is ~70 and ~10-fold selective versus JAK3 and Tyk2, with no inhibition to c-Met and... MSRP: Was: Now: $949 - $2,898 Choose Options Compare
Quick view Biovision | WP1066 | 1809 A potent, cell-permeable JAK2 inhibitor. A novel analog of the JAK2 inhibitor AG490 (Cat. No. 1570-5) that blocks STAT3 and phosphoinositide-3-kinase pathways. It is significantly more potent and... MSRP: Was: Now: $865 - $2,555 Choose Options Compare
Quick view Biovision | Ivermectin | 2721 Ivermectin is an antiparasitic agent. It acts as a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.Ivermectin... MSRP: Was: Now: $665 - $1,411 Choose Options Compare
Quick view Biovision | Eltrombopag | 9489 Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet... MSRP: Was: Now: $837 - $2,440 Choose Options Compare
Quick view Biovision | Dynasore | 1900 Cell-permeable. A reversible, noncompetitive inhibitor of dynamin that interferes in vitro with the GTPase activity of dynamin1, dynamin2, and Drp1, the mitochondrial dynamin, but not of other small... MSRP: Was: Now: $665 - $1,523 Choose Options Compare
Quick view Biovision | Skepinone-L | B1110 Skepinone-L is a potent, ATP-competitive inhibitor of p38 MAPK isoform p38α (IC₅₀ = 5 nM) and p38β (97% inhibition at 1 µM). It has little effect on a range of other kinases, including p38γ and p38δ... MSRP: Was: Now: $837 - $2,440 Choose Options Compare
Quick view Biovision | Vesnarinone | B2008 Vesnarinone is a novel inotropic agent that displays unique and complex mechanisms of action. It inhibits phosphodiesterase, thereby leading to increased intracellular calcium, and also affects... MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare
Quick view Biovision | Vonoprazan fumarate | B2292 Vonoprazan fumarate is a Potassium-competitive acid blocker (P-CAB) that inhibits gastric H⁺/K⁺ATPase (IC₅₀ = 17 nM) but does not inhibit porcine Na+/K+ ATPase activity when used at a concentration... MSRP: Was: Now: $718 - $1,582 Choose Options Compare
Quick view Biovision | CZC24832 | B1676 CZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154... MSRP: Was: Now: $949 - $2,870 Choose Options Compare
Quick view Biovision | Prasugrel | 9472 Prasugrel is novel thienopyridine antiplatelet prodrug that is metabolized to the thiol-containing active metabolite R-138727,which binds to and irreversibly inhibits the platelet P2Y12ADP receptor... MSRP: Was: Now: $718 - $1,985 Choose Options Compare
Quick view Biovision | E-64 | 1739 E-64 is an irreversible, cell-permeable, potent, and highly selective cysteine protease inhibitor. E-64 will not inhibit serine proteases (except trypsin) like other cysteine protease inhibitors,... MSRP: Was: Now: $1,036 - $2,930 Choose Options Compare
Quick view Biovision | Epothilone D | 9559 Epothilone D is a natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the... MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare
Quick view Biovision | UNC0638 | 1933 Cell-permeable. UNC0638 is a potent G9a HMTase inhibitor, exhibiting an IC₅₀ value of MSRP: Was: Now: $749 - $1,463 Choose Options Compare
Quick view Biovision | WAY-600 | B1731 WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold)... MSRP: Was: Now: $837 - $1,866 Choose Options Compare
Quick view Biovision | WYE-687 | B1730 WYE-687 is an ATP-competitive and selective inhibitor of mTOR with an IC50 value of 7 nM.WYE-687 is an ATP-competitive and selective inhibitor of mTOR with an IC50 value of 7 nM.Biovision | B1730 |... MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare
Quick view Biovision | BMS-911543 | 2630 BMS-911543 is a potent and selective JAK2 inhib itor. It displays potent anti-proliferative and pharmacodynamic effects in cell lines dependent upon JAK2 signaling, and has little activity in cell... MSRP: Was: Now: $777 - $2,209 Choose Options Compare
Quick view Biovision | CP-640186 | 9422 CP-640186 is a mixed ACC (Acetyl-CoA carboxylase) inhibitor (ACC-1 IC₅₀ = 53 nM; ACC-2 IC₅₀ = 61 nM) that lowers malonyl-CoA levels and inhibits hepatic fatty acid and triglyceride synthesis in vitro... MSRP: Was: Now: $1,008 - $2,958 Choose Options Compare
Quick view Biovision | Tiplaxtinin | B1634 Tiplaxtinin(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 µM.Tiplaxtinin(PAI-039) is a selective and orally efficacious... MSRP: Was: Now: $865 - $2,587 Choose Options Compare
Quick view Biovision | JZL195 | B1064 JZL195 is a potent dual inhibitor of Monoacylglycerol lipase (MAGL) (IC₅₀ = 2 nM) and fatty acid amide hydrolase (FAAH) (IC₅₀ = 4 nM), enzymes that degrade the endocannabinoids 2-arachidonoylglycerol... MSRP: Was: Now: $777 - $2,209 Choose Options Compare
Quick view Biovision | GDC-0349 | B1729 GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki value of 3.8 nM.GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki value of 3.8 nM.Biovision |... MSRP: Was: Now: $837 - $1,866 Choose Options Compare
Quick view Biovision | GSK2636771 | 2793 GSK2636771 is a potent, PI3Kβ-selective inhibitor, sensitive to PTEN cell lines.GSK2636771 is a potent, PI3Kβ-selective inhibitor, sensitive to PTEN cell lines.Biovision | 2793 | GSK2636771... MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare
Quick view Biovision | Alpelisib | B1271 Alpelisib (also known as BYL719), is a potent and selective phosphatidylinositol-3 kinase α inhibitor. It inhibits P110α, p110β, p110δ, and p110g with IC₅₀ values of 5 nM, 1.2 µM, 0.29 µM and 0.25... MSRP: Was: Now: $949 - $2,898 Choose Options Compare
Quick view Biovision | Geldanamycin | 1564 A potent antitumor antibiotic . Binds specifically to heat shock protein HSP90 and its GP96 homologue; inhibits protein maturation.Geldanamycin is a potent antitumor antibiotic . Binds specifically... MSRP: Was: Now: $777 - $2,065 Choose Options Compare
Quick view Biovision | EPZ004777 | 2381 A potent and selective DOT1L inhibitor. Treatment of leukemic cells with EPZ004777 results in selective killing of those cells bearing the MLL (mixed lineage leukemia) gene translocation, with little... MSRP: Was: Now: $949 - $2,555 Choose Options Compare
Quick view Biovision | MI-3 | B1834 MI-3 is a Menin-MLL (Mixed linage leukemia) protein interaction inhibitor with an IC₅₀ of 648 ± 25 nM. MLL protein is a histone methyltransferase that positively regulates gene transcription... MSRP: Was: Now: $1,061 - $3,385 Choose Options Compare
Quick view Biovision | MI-2 | B1835 MI-2 is a Menin-MLL (Mixed linage leukemia) protein interaction inhibitor with an IC₅₀ of 0.45 μM. MLL protein is a histone methyltransferase that positively regulates gene transcription. However,... MSRP: Was: Now: $1,061 - $3,385 Choose Options Compare
Quick view Biovision | Repaglinide | B2110 Repaglinide is an antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which... MSRP: Was: Now: $718 - $1,925 Choose Options Compare
Quick view Biovision | Glibenclamide | 1878 Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin... MSRP: Was: Now: $690 - $980 Choose Options Compare
Quick view Biovision | PF-04691502 | 2289 A potent, ATP-competitive PI3K/mTOR dual inhibitor with broad antitumor activity. PF-04691502 potently inhibits recombinant class I PI3K and mTOR in biochemical assays and suppresses transformation... MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare
Quick view Biovision | Ro3280 | B1175 RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1 (IC₅₀ = 3 nM).RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1 (IC₅₀ = 3 nM).Biovision | B1175 |... MSRP: Was: Now: $1,239 - $4,018 Choose Options Compare
Quick view Biovision | Staurosporine | 1048 Potent inhibitor of protein kinase C and most other kinases, including tyrosine kinases. Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site... MSRP: Was: Now: $949 - $2,209 Choose Options Compare
Quick view Biovision | Lonafarnib | B1616 Lonafarnib (SCH 66336) is a selectively farnesyltransferase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.Lonafarnib (SCH 66336) is a selectively... MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare
Quick view Details Biovision | CH5132799 | B1669 MSRP: Was: Now: $865 - $2,587 Choose Options Compare
Quick view Details Biovision | Ertugliflozin | B1896 MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare
Quick view Details Biovision | CHIR-090 | B1852 MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare
Quick view Details Biovision | Cabazitaxel | B2399 MSRP: Was: Now: $718 - $1,866 Choose Options Compare
Quick view Details Biovision | Triciribine | 1707 MSRP: Now: $1,120 Add to Cart Compare Quick view Details Biovision | Roflumilast | 2675 MSRP: Was: Now: $777 - $2,209 Choose Options Compare Quick view Details Biovision | PF-04447943 | B1264 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Details Biovision | SL327 | B1694 MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Details Biovision | MK-0557 | B2317 MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare Quick view Details Biovision | Empagliflozin | 2877 MSRP: Was: Now: $1,008 - $2,555 Choose Options Compare Quick view Details Biovision | Tazarotene | B1812 MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Details Biovision | Fenretinide | 9417 MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare Quick view Details Biovision | Forskolin | 1531 MSRP: Was: Now: $809 - $2,209 Choose Options Compare Quick view Details Biovision | Tetrahydrouridine | 1671 MSRP: Was: Now: $1,152 - $20,440 Choose Options Compare Quick view Details Biovision | CVT-313 | B1137 MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Details Biovision | TG003 | 1905 MSRP: Was: Now: $865 - $2,499 Choose Options Compare Quick view Details Biovision | Etoricoxib | B1983 MSRP: Was: Now: $777 - $2,156 Choose Options Compare Quick view Details Biovision | RI-1 | B1823 MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Details Biovision | Baricitinib | 2842 MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Details Biovision | WP1066 | 1809 MSRP: Was: Now: $865 - $2,555 Choose Options Compare Quick view Details Biovision | Ivermectin | 2721 MSRP: Was: Now: $665 - $1,411 Choose Options Compare Quick view Details Biovision | Eltrombopag | 9489 MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Details Biovision | Dynasore | 1900 MSRP: Was: Now: $665 - $1,523 Choose Options Compare Quick view Details Biovision | Skepinone-L | B1110 MSRP: Was: Now: $837 - $2,440 Choose Options Compare Quick view Details Biovision | Vesnarinone | B2008 MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare Quick view Details Biovision | Vonoprazan fumarate | B2292 MSRP: Was: Now: $718 - $1,582 Choose Options Compare Quick view Details Biovision | CZC24832 | B1676 MSRP: Was: Now: $949 - $2,870 Choose Options Compare Quick view Details Biovision | Prasugrel | 9472 MSRP: Was: Now: $718 - $1,985 Choose Options Compare Quick view Details Biovision | E-64 | 1739 MSRP: Was: Now: $1,036 - $2,930 Choose Options Compare Quick view Details Biovision | Epothilone D | 9559 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Details Biovision | UNC0638 | 1933 MSRP: Was: Now: $749 - $1,463 Choose Options Compare Quick view Details Biovision | WAY-600 | B1731 MSRP: Was: Now: $837 - $1,866 Choose Options Compare Quick view Details Biovision | WYE-687 | B1730 MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare Quick view Details Biovision | BMS-911543 | 2630 MSRP: Was: Now: $777 - $2,209 Choose Options Compare Quick view Details Biovision | CP-640186 | 9422 MSRP: Was: Now: $1,008 - $2,958 Choose Options Compare Quick view Details Biovision | Tiplaxtinin | B1634 MSRP: Was: Now: $865 - $2,587 Choose Options Compare Quick view Details Biovision | JZL195 | B1064 MSRP: Was: Now: $777 - $2,209 Choose Options Compare Quick view Details Biovision | GDC-0349 | B1729 MSRP: Was: Now: $837 - $1,866 Choose Options Compare Quick view Details Biovision | GSK2636771 | 2793 MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare Quick view Details Biovision | Alpelisib | B1271 MSRP: Was: Now: $949 - $2,898 Choose Options Compare Quick view Details Biovision | Geldanamycin | 1564 MSRP: Was: Now: $777 - $2,065 Choose Options Compare Quick view Details Biovision | EPZ004777 | 2381 MSRP: Was: Now: $949 - $2,555 Choose Options Compare Quick view Details Biovision | MI-3 | B1834 MSRP: Was: Now: $1,061 - $3,385 Choose Options Compare Quick view Details Biovision | MI-2 | B1835 MSRP: Was: Now: $1,061 - $3,385 Choose Options Compare Quick view Details Biovision | Repaglinide | B2110 MSRP: Was: Now: $718 - $1,925 Choose Options Compare Quick view Details Biovision | Glibenclamide | 1878 MSRP: Was: Now: $690 - $980 Choose Options Compare Quick view Details Biovision | PF-04691502 | 2289 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Quick view Details Biovision | Ro3280 | B1175 MSRP: Was: Now: $1,239 - $4,018 Choose Options Compare Quick view Details Biovision | Staurosporine | 1048 MSRP: Was: Now: $949 - $2,209 Choose Options Compare Quick view Details Biovision | Lonafarnib | B1616 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare Previous 182 183 184 185 186 187 188 189 190 191 192 Next Previous 182 183 184 185 186 187 188 189 190 191 192 Next Compare Selected
Quick view Details Biovision | Roflumilast | 2675 MSRP: Was: Now: $777 - $2,209 Choose Options Compare
Quick view Details Biovision | PF-04447943 | B1264 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare
Quick view Details Biovision | MK-0557 | B2317 MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare
Quick view Details Biovision | Empagliflozin | 2877 MSRP: Was: Now: $1,008 - $2,555 Choose Options Compare
Quick view Details Biovision | Tazarotene | B1812 MSRP: Was: Now: $949 - $2,898 Choose Options Compare
Quick view Details Biovision | Fenretinide | 9417 MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare
Quick view Details Biovision | Tetrahydrouridine | 1671 MSRP: Was: Now: $1,152 - $20,440 Choose Options Compare
Quick view Details Biovision | Etoricoxib | B1983 MSRP: Was: Now: $777 - $2,156 Choose Options Compare
Quick view Details Biovision | Baricitinib | 2842 MSRP: Was: Now: $949 - $2,898 Choose Options Compare
Quick view Details Biovision | Ivermectin | 2721 MSRP: Was: Now: $665 - $1,411 Choose Options Compare
Quick view Details Biovision | Eltrombopag | 9489 MSRP: Was: Now: $837 - $2,440 Choose Options Compare
Quick view Details Biovision | Skepinone-L | B1110 MSRP: Was: Now: $837 - $2,440 Choose Options Compare
Quick view Details Biovision | Vesnarinone | B2008 MSRP: Was: Now: $1,120 - $3,584 Choose Options Compare
Quick view Details Biovision | Vonoprazan fumarate | B2292 MSRP: Was: Now: $718 - $1,582 Choose Options Compare
Quick view Details Biovision | Epothilone D | 9559 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare
Quick view Details Biovision | WYE-687 | B1730 MSRP: Was: Now: $1,061 - $3,357 Choose Options Compare
Quick view Details Biovision | BMS-911543 | 2630 MSRP: Was: Now: $777 - $2,209 Choose Options Compare
Quick view Details Biovision | CP-640186 | 9422 MSRP: Was: Now: $1,008 - $2,958 Choose Options Compare
Quick view Details Biovision | Tiplaxtinin | B1634 MSRP: Was: Now: $865 - $2,587 Choose Options Compare
Quick view Details Biovision | GSK2636771 | 2793 MSRP: Was: Now: $1,008 - $3,129 Choose Options Compare
Quick view Details Biovision | Alpelisib | B1271 MSRP: Was: Now: $949 - $2,898 Choose Options Compare
Quick view Details Biovision | Geldanamycin | 1564 MSRP: Was: Now: $777 - $2,065 Choose Options Compare
Quick view Details Biovision | Repaglinide | B2110 MSRP: Was: Now: $718 - $1,925 Choose Options Compare
Quick view Details Biovision | Glibenclamide | 1878 MSRP: Was: Now: $690 - $980 Choose Options Compare
Quick view Details Biovision | PF-04691502 | 2289 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare
Quick view Details Biovision | Staurosporine | 1048 MSRP: Was: Now: $949 - $2,209 Choose Options Compare
Quick view Details Biovision | Lonafarnib | B1616 MSRP: Was: Now: $1,292 - $4,277 Choose Options Compare
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