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Product Description
Recombinant Human VCAM1 Protein, hFc-tagged, FITC conjugated | VCAM1-1794MF | Creative BioMart
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Bio-activity :
Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells.
Endotoxin :
< 0.06 EU/ μg as determined by LAL test.
Purity :
> 98 % by SDS-PAGE under reducing conditions.
Characteristic :
Disulfide-linked homodimer
Labeled with FITC via amines
Excitation source: 488 nm spectral line, argon-ion laser
Excitation Wavelength: 488 nm
Emission Wavelength: 535 nm
Stability :
Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade.
Storage Buffer :
Lyophilized from 0.2 μm filtered solution in PBS.
Reconstitution :
Reconstitute at 100 μg/mL in sterile PBS.
