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Product Description
Anti-Human CD11a Monoclonal Antibody (PE Conjugated) | DL22233F | DLdevelop
Host: Mouse
Synonyms: Integrin alpha-L, LFA-1A, CD11A, ITGAL
Reactivity: Human
Application: FCM
Background: CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .
Concentration: N/A
Conjugation: PE
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: R7-1
Isotype: Mouse IgG1, κ
