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Product Description
Anti-Human CD11b Monoclonal Antibody (AF647 Conjugated) | DL21786F | DLdevelop
Host: Mouse
Synonyms: Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b
Reactivity: Human
Application: FCM
Background: CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
Concentration: N/A
Conjugation: AF647
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: ICRF44
Isotype: Mouse IgG1, κ
