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Product Description
Anti-Human CD27 Monoclonal Antibody (AF488 Conjugated) | DL21736F | DLdevelop
Host: Mouse
Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, S152, TNFRSF7
Reactivity: Human
Application: FCM
Background: CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Concentration: N/A
Conjugation: AF488
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: O323
Isotype: Mouse IgG1, κ
