Product Description
Anti-Human CD41 Monoclonal Antibody (AF488 Conjugated) | DL20995F | DLdevelop
Host: Mouse
Synonyms: Integrin alpha-Iib, ITGA2B, GPalpha Iib, GPIIb, Platelet membrane glycoprotein Iib, CD41, GP2B, ITGAB
Reactivity: Human
Application: FCM
Background: CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.
Concentration: N/A
Conjugation: AF488
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: HIP8
Isotype: Mouse IgG1, κ