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Product Description
Anti-Human CD53 Monoclonal Antibody (Biotin Conjugated) | DL20617F | DLdevelop
Host: Mouse
Synonyms: Leukocyte surface antigen CD53, CD53, Cell surface glycoprotein CD53, Tetraspanin-25, Tspan-25, MOX44, TSPAN25
Reactivity: Human
Application: FCM
Background: CD53 is a 35-42 kD type III tetraspan membrane protein. It is expressed on all leukocytes, but not on platelets or erythrocytes. CD53 is thought to be involved in signal transduction. It has been shown to interact with a number of proteins including IL-4, CD20, CD2, CD9, IL-2, VLA-4, and CD4. Cross-linking of CD53 promotes B cell activation. The CD53 antigen is highly glycosylated and treatment with endoglycosidase F reduces the apparent molecular weight of this protein by approximately 25 kD.
Concentration: 0.5 mg/mL
Conjugation: Biotin
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: C53-2
Isotype: Mouse IgG2a, κ
