Product Description
Anti-Human CD69 Monoclonal Antibody (AF647 Conjugated) | DL21716F | DLdevelop
Host: Mouse
Synonyms: Early activation antigen CD69, Activation inducer molecule, AIM, EA1, MLR-5
Reactivity: Human
Application: FCM
Background: CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.
Concentration: N/A
Conjugation: AF647
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: FN50
Isotype: Mouse IgG1, κ