Product Description
Anti-Mouse CD45.1 Monoclonal Antibody (PE Conjugated) | DL22015F | DLdevelop
Host: Mouse
Synonyms: Ly-5, L-CA, T200, CD45, Ptprc
Reactivity: Mouse
Application: FCM
Background: CD45.1 is an alloantigen of CD45, expressed by Ly5.1 bearing mouse strains (e.g., RIII, SJL/J, STS/A, DA) . CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in mice that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell types. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Concentration: N/A
Conjugation: PE
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: A20
Isotype: Mouse IgG2a, κ