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Product Description
Anti-Mouse IL-10 Monoclonal Antibody (APC Conjugated) | DL22153F | DLdevelop
Host: Rat
Synonyms: Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF
Reactivity: Mouse
Application: ICFCM
Background: L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production) ; and promotes mast cell proliferation in combination with IL-4.
Concentration: N/A
Conjugation: APC
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: JES5-16E3
Isotype: Rat IgG2b, κ
