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Product Description
Purified Anti-Human CD58 Monoclonal Antibody | DL20838F | DLdevelop
Host: Mouse
Synonyms: Lymphocyte function-associated antigen 3, CD58, Ag3, Surface glycoprotein LFA-3, LFA3
Reactivity: Human
Application: FCM, IP
Background: CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI) -anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.
Concentration: 0.2 mg/mL
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Clone: TS2/9.1
Isotype: Mouse IgG1, κ
