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Product Description
HLA-F Polyclonal Antibody | E-AB-65765 | Elabscience
Type: Polyclonal Antibody
Synonyms: HLA-F, CDA12, HLA-5.4, HLA-CDA12, HLAF
Application: WB
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: N/A
Background: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human HLA-F (NP_001091949.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 28 kDa/39 kDa/50 kDa
Molecular Weight(Observed): 50 kDa
