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Product Description
UBXN1 Polyclonal Antibody | E-AB-18676 | Elabscience
Type: Polyclonal Antibody
Synonyms: 2B28, 4930455J02Rik, D19Ertd721e, MGC124706, MGC6696, mY33K, Protein 2B28, RGD1309471, SAKS1, SAPK substrate protein 1, T25529, UBA/UBX 33.3 kDa protein, UBX domain containing protein 1, UBX domain protein 1, UBXD10, UBXN1
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell Biology, Signal transduction
Background: Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
Concentration: 1.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Full length fusion protein
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 33 kDa
Molecular Weight(Observed): Refer to figures
