Product Description
GM2A Polyclonal Antibody | E-AB-67777 | Elabscience
Type: Polyclonal Antibody
Synonyms: GM2A, GM2-AP, SAP-3
Application: WB
Reactivity: Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal Transduction
Background: This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human GM2A (NP_000396.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 20 kDa
Molecular Weight(Observed): 26 kDa