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Product Description
GSTM2 Polyclonal Antibody | E-AB-40444 | Elabscience
Type: Polyclonal Antibody
Synonyms: Glutathione S alkyltransferase M2, Glutathione S transferase 4, Glutathione S transferase M1, GST class mu 2, GST muscle, GST4, GSTM, GSTM2, GTHMUS
Application: WB
Reactivity: Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Signal Transduction, Metabolism
Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
Concentration: 0.14 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Rat Glutathione S-transferase Mu 2 protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Purification Method: Antigen Affinity Purification
Dilution: WB 1:500-1:1000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 25 kDa
Molecular Weight(Observed): 25 kDa
