Product Description
DSC2 Polyclonal Antibody | E-AB-13194 | Elabscience
Type: Polyclonal Antibody
Synonyms: ARVD11, Cadherin family member 2, CDHF2, Desmocollin 3, Desmocollin-2, Desmocollin-3, Desmocollin2, Desmosomal glycoprotein II and III, Desmosomal glycoprotein II, Desmosomal glycoprotein II/III, Desmosomal glycoprotein III, DG2, DGII/III, DKFZp686I11137, DSC 2, DSC2, DSC2, DSC3
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cardiovascular, Signal Transduction
Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.
Concentration: 0.7 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human DSC2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A