Euro
USD
British Pound
NULL
Product Description
Phospho-PDGFR beta(Y740) Polyclonal Antibody | E-AB-68182 | Elabscience
Type: Phosphorylated antibody
Synonyms: CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT, PDGF Receptor beta, PDGFRB, PDGFR beta
Application: WB
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cardiovascular, Signal Transduction
Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: A synthetic phosphorylated peptide around Y740 of human PDGFR beta (NP_002600.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 37 kDa/123 kDa
Molecular Weight(Observed): 180 kDa
