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Product Description
SESN3 Polyclonal Antibody | E-AB-63213 | Elabscience
Type: Polyclonal Antibody
Synonyms: SESN3, SEST3, sestrin-3
Application: WB
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism
Background: This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human SESN3 (NP_653266.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:200-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 36 kDa/41 kDa/57 kDa
Molecular Weight(Observed): 50 kDa
