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![AF647 Anti-Human CD28 Antibody[CD28.2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/438739/641386/elabscience__13538.1643193164__44410.1643194172__86336.1647344788.png?c=2 "AF647 Anti-Human CD28 Antibody[CD28.2]")
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Product Description
AF647 Anti-Human CD28 Antibody[CD28.2] | E-AB-F1195M | Elabscience
Category: Flowcytometry Antibody
Synonyms: PAS2,MNS,HGpMiX,GYPA,GPSAT
Swissprot Code: P10747
Application: FCM
Reactivity: Mouse
Host: Rat
Isotype: Rat IgG2b, κ
Research Areas: Cancer, Immunology, Stem cells
Backgroun: CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
Concentration: N/A
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Buffer: PBS with 0.05% Proclin300, 1% BSA
Purification Method: N/A
Dilution: N/A
Clone: CD28.2
Conjugation: AF647
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A
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