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![AF647 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/438288/640692/elabscience__13538.1643193164__44410.1643194172__10938.1647344431.png?c=2 "AF647 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]")
. Unstained splenocytes (empty black histogram) are used as control.](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/438288/640693/E-AB-F1131UM-FC01__24515.1647344431.jpg?c=2 "Con-A stimulated C57BL/6 splenocytes (3 days) are stained with AF647 Anti-Mouse CD279/PD-1 Antibody[Used at .2 μg/1<sup>6</sup> cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.")
![AF647 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/438288/640692/elabscience__13538.1643193164__44410.1643194172__10938.1647344431.png?c=2 "AF647 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]")
. Unstained splenocytes (empty black histogram) are used as control.](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/438288/640693/E-AB-F1131UM-FC01__24515.1647344431.jpg?c=2 "Con-A stimulated C57BL/6 splenocytes (3 days) are stained with AF647 Anti-Mouse CD279/PD-1 Antibody[Used at .2 μg/1<sup>6</sup> cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.")
Product Description
AF647 Anti-Mouse CD279/PD-1 Antibody[29F.1A12] | E-AB-F1131UM | Elabscience
Category: Flowcytometry Antibody
Synonyms: PD-1, Programmed Death-1
Swissprot Code: Q02242
Application: FCM
Reactivity: Mouse
Host: Rat
Isotype: Rat IgG2a, κ
Research Areas: Cancer, Cell Biology, Immunology
Backgroun: CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
Concentration: 0.5 mg/mL
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Buffer: PBS with 0.05% Proclin300, 1% BSA
Purification Method: N/A
Dilution: N/A
Clone: 29F.1A12
Conjugation: AF647
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A
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