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![PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] | E-AB-F1235UH](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/439207/641996/elabscience__13538.1643193164__44410.1643194172__70996.1647355423.png?c=2 "PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] | E-AB-F1235UH")
. Unstained bone marrow cells(empty black histogram) are used as control.](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/439207/641997/E-AB-F1235UH-FC01__57470.1647345068.jpg?c=2 "C57BL/6 murine bone marrow cells are stained with PE/Cyanine7 Anti-Mouse CD51 Antibody[Used at .2 μg/1<sup>6</sup> cells dilution](filled gray histogram). Unstained bone marrow cells(empty black histogram) are used as control.")
![PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] | E-AB-F1235UH](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/439207/641996/elabscience__13538.1643193164__44410.1643194172__70996.1647355423.png?c=2 "PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] | E-AB-F1235UH")
. Unstained bone marrow cells(empty black histogram) are used as control.](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/439207/641997/E-AB-F1235UH-FC01__57470.1647345068.jpg?c=2 "C57BL/6 murine bone marrow cells are stained with PE/Cyanine7 Anti-Mouse CD51 Antibody[Used at .2 μg/1<sup>6</sup> cells dilution](filled gray histogram). Unstained bone marrow cells(empty black histogram) are used as control.")
Product Description
PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] | E-AB-F1235UH | Elabscience
Category: Flow Cytometry Antibody
Synonyms: Integrin alpha-V ,αV integrin, Vitronectin Receptor, Integrin αV chain, ITGAV
Swissprot Code: P43406
Application: FCM
Reactivity: Mouse
Host: Rat
Isotype: Rat IgG1, κ
Reaserch Area: N/A
Background: CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
Concentration: 0.2 mg/mL
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Purification Method: N/A
Dilution: N/A
Clone: RMV-7
Conjugation: PE/Cyanine7
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