Product Description
NANOS2 Polyclonal Antibody | E-AB-11419 | Elabscience
Type: Polyclonal Antibody
Synonyms: NANO2, Nanos homolog 2, Nanos homolog 2 Drosophila, NANOS2, NOS-2, NOS2
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells
Background: Nanos2, also known as NOS2, is a 138 amino acid protein that contains one nanos-type zinc finger. The nanos-type zinc finger is comprised of two C2HC motifs, each of which are capable of binding one molecule of zinc and each of which work in tandem to play essential roles in translational regulation events. Expressed specifically in male germ cells, Nanos2 is essential for spermatogonia formation and is required to support the self-renewal, proliferation and overall development of proximal germ cells. Additionally, Nanos2 is thought to regulate the translation of target mRNAs, possibly by associating with the 3’-UTR of select transcripts.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human NANOS2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A