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Product Description
Phospho-IGF1R(Y1161) Polyclonal Antibody | E-AB-68139 | Elabscience
Type: Phosphorylated antibody
Synonyms: IGF1R, CD221, IGFIR, IGFR, JTK13
Application: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Developmental Biology, Signal Transduction
Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: A phospho specific peptide corresponding to residues surrounding Y1161 of human IGF1R
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 154 kDa
Molecular Weight(Observed): 95 kDa
