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Product Description
ACMSD Polyclonal Antibody | E-AB-10712 | Elabscience
Type: Polyclonal Antibody
Synonyms: 2 amino 3 carboxymuconate 6 semialdehyde decarboxylase, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, acmsd, ACMSD, Aminocarboxymuconate semialdehyde decarboxylase, Picolinate carboxylase
Application: WB, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal Transduction
Background: The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Concentration: 0.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human ACMSD
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 38 kDa
Molecular Weight(Observed): N/A
