Product Description
CRMP1 Polyclonal Antibody | E-AB-12333 | Elabscience
Type: Polyclonal Antibody
Synonyms: Collapsin response mediator protein 1, CRMP 1, CRMP-1, Crmp1, Dihydropyrimidinase like 1, Dihydropyrimidinase related protein 1, Dihydropyrimidinase-related protein 1, DPYL1, DPYSL1, DRP 1, DRP-1, DRP1, ULIP-3, Ulip3, Unc-33-like phosphoprotein 3
Application: WB, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Neuroscience, Signal Transduction
Background: Collapsin response mediator protein 1, encoded by theCRMP1gene, is a humanproteinof theCRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human CRMP1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 62 kDa
Molecular Weight(Observed): N/A