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Product Description
NFKBID Polyclonal Antibody | E-AB-10087 | Elabscience
Type: Polyclonal Antibody
Synonyms: I-kappa-B-delta, IkappaBdelta, IkappaBNS, IkB-delta, IKBD, IKBNS, NF-kappa-B inhibitor delta, NFKBID, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor delta, T-cell activation NFKB-like protein, TA-NFKBH
Application: WB, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
Background: May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human NFKBID
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 33 kDa
Molecular Weight(Observed): N/A
