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Product Description
TAB3 Polyclonal Antibody | E-AB-11380 | Elabscience
Type: Polyclonal Antibody
Synonyms: MAP3K7IP 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NAP1, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, Tab3, TAB3, TAK1 binding protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1-binding protein 3
Application: WB, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
Background: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.
Concentration: 0.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human TAB3
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 79 kDa
Molecular Weight(Observed): N/A
