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Product Description
SETMAR Polyclonal Antibody | E-AB-18994 | Elabscience
Type: Polyclonal Antibody
Synonyms: Histone lysine N methyltransferase, Histone lysine N methyltransferase SETMAR, Hsmar 1, Hsmar1, Mariner transposase Hsmar1, Metnase, SET domain and mariner transposase fusion, SET domain and mariner transposase fusion gene, SET domain and mariner transposase fusion gene containing protein, SET domain and mariner transposase fusion gene-containing protein, Setmar, SETMR
Application: IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling
Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Concentration: 1.08 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human SETMAR
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A
