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Product Description
ZNF486 Polyclonal Antibody | E-AB-18362 | Elabscience
Type: Polyclonal Antibody
Synonyms: KRAB box only protein 2 , KRBO2 , Zinc finger protein 486
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF486 (Zinc finger protein 486), also known as KRAB domain only protein 2, is a 216 amino acid nuclear protein that contains one KRAB domain and two C2H2-type zinc fingers. The gene encoding ZNF486 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1, 400 genes and is recognized for having the greatest gene density of the human chromosomes. May be involved in transcriptional regulation.
Concentration: 0.9 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human ZNF486
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:40-1:250, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A
