Product Description
Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5] | E-AB-F1124A | Elabscience
Category: Flowcytometry Antibody
Synonyms: TCR-γ/δ, γ/δ TCR
Swissprot Code: N/A
Application: FCM,IP
Reactivity: Mouse
Host: Rat
Isotype: Rat IgG2b, κ
Research Areas: N/A
Backgroun: T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo.
Concentration: 0.5 mg/mL
Storage: Store at 2~8°C. Do not freeze.
Immunogen: N/A
Buffer: PBS with 0.05% Proclin300
Purification Method: N/A
Dilution: N/A
Clone: UC7-13D5
Conjugation: Unconjugated
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A