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![AF/LE Purified Anti-Human CD8a Antibody[OKT-8]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/438003/640214/elabscience__13538.1643193164__44410.1643194172__20005.1647344204.png?c=2 "AF/LE Purified Anti-Human CD8a Antibody[OKT-8]")
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Product Description
AF/LE Purified Anti-Human CD8a Antibody[OKT-8] | E-AB-F11100 | Elabscience
Category: Flowcytometry Antibody
Synonyms: T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL
Swissprot Code: P01732
Application: Depletion, FCM
Reactivity: Human
Host: Mouse
Isotype: Mouse IgG2a, κ
Research Areas: Cancer, Immunology, Stem cells
Backgroun: CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Concentration: 0.5 mg/mL
Storage: Store at 2~8°C. Do not freeze.
Immunogen: N/A
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Purification Method: N/A
Dilution: N/A
Clone: OKT-8
Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A
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