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Product Description
DMBT1 Polyclonal Antibody | E-AB-40467 | Elabscience
Type: Polyclonal Antibody
Synonyms: Apactin, CRP, Crpd, DBMT1, Deleted in malignant brain tumors 1 protein, DMBT1, DMBT1 prototype precursor, Ebnerin, FLJ61058, Glycoprotein 300, Glycoprotein 340, GP340, Gp340 variant protein, GP340, Hensin, MGC164738, Muclin, p80, Pancrin, SAG, Salivary agglutinin, Surfactant pulmonary associated D binding protein, Vomeroglandin
Application: IHC
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Signal Transduction
Background: Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Concentration: 0.71mg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human Deleted in malignant brain tumors 1 protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification Method: Antigen Affinity Purification
Dilution: IHC 1:200-1:500
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A
