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Product Description
COX-2 Monoclonal Antibody | PA6678 | Elabscience
Clone: YN00555m
Reactivity: Human
Host: Mouse
Application: Immunohistochemistry-P
Category Type: RTU for IHC
Swissprot: P35354
Concentration: 100μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody
Buffer: TBS with 0.1% Proclin300, PH7.4
Background: Cox-2 is an inducible enzyme which can be involved in the cell reactions of growth factors, tumor promoters and cytokines, all of those factors can induce cox-2 overexpression. Cox-2 is also involved in the synthesis of prostaglandins. Cox-2 expression is significantly increased in 85-90% in colorectal adenocarcinoma patients, while cox-1 expression is unchanged.
Location: Cell membrane,Cytoplasm
