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Product Description
JAK3 Polyclonal Antibody | E-AB-31846 | Elabscience
Type: Polyclonal Antibody
Synonyms: EC 2.7.10.2, JAK 3, JAK L, JAK-3, Jak3, JAK3 HUMAN, JAK3, JAKL, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3, Janus Kinase3, L JAK, L-JAK, Leukocyte janus kinase, LJAK, Protein tyrosine kinase leukocyte, Tyrosine protein kinase JAK3, Tyrosine-protein kinase JAK3
Application: WB, IHC-p, IF, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Tyr785.
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 125 kDa
Molecular Weight(Observed): 125 kDa
