Product Description
RNF8 Polyclonal Antibody | E-AB-66211 | Elabscience
Type: Polyclonal Antibody
Synonyms: RNF8, hRNF8
Application: IF
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: N/A
Background: The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human RNF8 (NP_003949.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: IF 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A