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Product Description
UMPS Polyclonal Antibody | E-AB-18508 | Elabscience
Type: Polyclonal Antibody
Synonyms: ODC, OMPdecase, OPRT, OPRTase, Orotate phosphoribosyl transferase and orotidine 5' decarboxylase, Orotate phosphoribosyltransferase, Orotate phosphoribosyltransferase phosphoribosyltransferase, Orotidine 5' phosphate decarboxylase, Orotidine 5''-phosphate decarboxylase, RP11-71H17.9, UMP synthase, Umps, UMPS, Uridine 5' monophosphate synthase, Uridine monophosphate synthetase
Application: IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling, Metabolism
Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human UMPS
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A
