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Product Description
SLC22A17 Polyclonal Antibody | E-AB-12870 | Elabscience
Type: Polyclonal Antibody
Synonyms: 24p3 receptor, 24p3R, BOCT, BOIT, Brain type organic cation transporter, Brain-type organic cation transporter, hBOIT, Lipocalin-2 receptor, Neutrophil gelatinase associated lipocalin receptor, Neutrophil gelatinase-associated lipocalin receptor, NGAL receptor, NgalR, NGALR2, NGALR3, OTTHUMP00000082690, OTTHUMP00000082691, Potent brain type organic ion transporter, S22AH, Slc22a17, Solute carrier family 22 member 17, Solute carrier family 22 organic cation transporter member 17
Application: IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal Transduction
Background: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human SLC22A17
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:25-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A
