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Product Description
STK40 Polyclonal Antibody | E-AB-14693 | Elabscience
Type: Polyclonal Antibody
Synonyms: 2310004N11Rik, MGC4796, OTTHUMP00000009948, OTTHUMP00000009951, RP11-268J15.4, Ser/Thr like kinase, Serine/threonine kinase 40, Serine/threonine protein kinase 40, SgK495, SHIK, SINK homologous serine/threonine protein kinase, SINK-homologous inhibitory kinase, STK 40, Sugen kinase 495
Application: IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction
Background: STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human STK40
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A
