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Product Description
ADRBK1 Polyclonal Antibody | E-AB-60399 | Elabscience
Type: Polyclonal Antibody
Synonyms: GRK2, ADRBK1, BARK1, BETA-ARK1
Application: WB, IHC
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Neuroscience, Signal Transduction
Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human ADRBK1 (NP_001610.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000 IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 79 kDa
Molecular Weight(Observed): 80 kDa
