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Product Description
CYCS Polyclonal Antibody | E-AB-40209 | Elabscience
Type: Polyclonal Antibody
Synonyms: Cytochrome C, Somatic, CYC, Cytochrome C, THC4, HCS.
Application: WB, IHC
Reactivity: Human, Bovine
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction
Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human Cytochrome c protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method: Affinity purification
Dilution: WB 1:1000-1:2000 IHC 1:100-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 12 kDa
Molecular Weight(Observed): 12 kDa
